If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. Diabetes treatment: Can cinnamon lower blood sugar? Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: It's not suggested to take St. John's wort if you take blood thinners. Some don't work well with prescription medicines. Available for Android and iOS devices. It also relaxes and widens blood vessels in your heart (coronary arteries) which increases the flow of blood to your heart muscle. It can cause your blood pressure to become dangerously low. Do not stop taking it without consulting your doctor. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Changing positions slowly can help lessen dizziness. This list covers only some interactions. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Isosorbide mononitrate. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Some don't work well with prescription medicines. include protected health information. government site. This risk may be even higher for certain groups. 2023 Lybrate, Inc. All rights reserved. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Isosorbide Mononitrate side effects by likelihood and severity. In: Current Medical Diagnosis & Treatment 2022. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. This drug may make you dizzy. Some of these medicine interactions can be risky. Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This is so your doctor can check on your progress. Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Mayo Clinic does not endorse companies or products. There are a number of medications that your doctor can prescribe in place of isosorbide mononitrate (Monoket). National Library of Medicine Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Continue to take isosorbide even if you feel well. B12 and folic acid is essential along with iron. Epub 2006 Mar 22. Each day, take the first dose when you wake up, then take the second dose 7 hours later. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). 2017; doi:10.1016/j.jacc.2016.11.078. 72% of reviewers reported a positive effect, while 12% reported a negative effect. Tolerance is more likely to happen if you don't take your dose at the same time every day. Do not stop taking isosorbide without talking to your doctor. An official website of the United States government. Do not change the dosing times unless directed by your doctor. 8600 Rockville Pike Isosorbide mononitrate (Monoket) is a nitrate vasodilator. Nitrates in the management of acute coronary syndrome. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. The information eHealthMe analyzes includes: Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. My EKG showed Assess your symptoms online with our free symptom checker. This is called tolerance, and it cannot be fixed by raising the dose of the medication. Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. Using this medicine with any of the following medicines is not recommended. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. If this worries you, talk to your doctor or pharmacist about other options. However, you should not flush this medication down the toilet. Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. I took this for 4 days, and my headaches were unbearable. Do not start, stop, or change the dosage of any medicines without your doctor's approval. All rights reserved. Be sure to talk to your health care provider before you take any herbal supplements if you take prescription medicines. . There are 195 drugs known to interact with Learn to reduce stress through mindful living. The use of the Truven Health products is at your sole risk. Isosorbide mononitrate works in two ways. 1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. Accessed Sept. 7, 2022. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. Advertising revenue supports our not-for-profit mission. A total of 195 drugs are known to interact with isosorbide mononitrate: A total of 330 drugs are known to interact with aspirin: A total of 239 drugs are known to interact with nitroglycerin: No known alcohol/food interactions. Mehta D. Botanical medicines. Am J Ther. Yes, it's good for health but don't take it excesse in amount, use once daily for 1 month then stop it or take once a weekly. information highlighted below and resubmit the form. Accessed Sept. 7, 2022. Take care, thanks. If your chest pain attacks happen more often, last longer, or become more severe at any time during your treatment, call your doctor. Try to keep your regular appointments with your doctor. Saper RB. Your doctor will prescribe you a short-acting nitrate for you to take if this happens. This does not necessarily mean no interactions exist. Otherwise, call a poison control center right away. Some of these medicine interactions can be risky. If you miss a dose, take it as soon as you remember. Herbal supplements are natural, so they must be safe, right? When used regularly on a long-term basis, this helps prevent angina attacks from occurring. If you buy any medicines, please check with a pharmacist that they are suitable for you to take with isosorbide mononitrate. Copyright 2023 IBM Watson Health. Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . Let your provider know if they are excessive. To help you remember, take it at the same times each day. Prescribed for Angina, Anal Fissure and Real test is coronary angiography. Isosorbide tablets are also used with other medications to treat heart failure. 67% of reviewers reported a positive effect, while 13% reported a negative effect. If you have an eye condition called glaucoma. it is a safe and effective alternative; the choice between beta blockers and calcium channel blockers depends . The effects of this exposure on a nursing infant are unknown. Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. This site complies with the HONcode standard for trustworthy health information: verify here. Swallow the tablet/capsule whole - do not chew or crush it before you swallow. Some of these interactions can be life-threatening. ask your doctor about the safe use of alcoholic beverages while you are taking isosorbide. Talk to your doctor about the possible risks of using this medication for your condition. 2021 May 11;39:28. doi: 10.11604/pamj.2021.39.28.22180. This site needs JavaScript to work properly. You can consult me online for homeopathic treatment. It does not work fast enough to relieve the pain of an angina attack that has already started. other information we have about you. Accessed Sept. 7, 2022. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. My blood pressure, cholesterol and pulse are all normal and I have no chest pains, shortness of breath or other heart problem symptoms. Talk to your provider if you notice your chest pain starts to get worse. Many people using this medication do not have serious side effects. The dose is according to the body weight and severity of the condition. Mehta D. Herbal & dietary supplements. We don't support your browser. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Important information about all medicines, Notes on Isosorbide mononitrate dose and side-effects info, https://patient.info/medicine/isosorbide-mononitrate-elantan-imdur-isotard-monomax-tardisc-xismox, Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets, Carmil XL; Chemydur XL; Elantan LA; Imdur; Isib XL; Ismo; Isodur XL; Isotard XL; Modisal XL; Monomax SR; Monomil XL; Nyzamac SR; Relosorb XL; Tardisc XL; Trangina XL; Xismox XL; Zemon XL, Tablets, modified-release (longer-acting) tablets, and modified-release (longer-acting) capsules, Ask your doctor or pharmacist to recommend a suitable painkiller. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price. Results: Licorice. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. Prescription and OTC I strongly feel that there is coronary ischemia. Your provider might temporarily have you stop isosorbide mononitrate (Monoket) if this happens. B complex. Always consult your healthcare provider. Liperoti R, et al. https://naturalmedicines.therapeuticresearch.com. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. . Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Some conditions may become worse when the drug is suddenly stopped. Avoid combinations; the risk of the interaction outweighs the benefit. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Does isosorbide mononitrate (Monoket) lower blood pressure? coma (loss of consciousness for a period of time). Browse Drugs and Medicines. Isosorbide mononitrate is a nitrate-class drug used for the prophylactic treatment of angina pectoris; that is, it is taken in order to prevent or at least reduce the occurrence of angina. There are no data on passage of isosorbide mononitrate in human milk, but some excretion seems likely. Accessed Sept. 7, 2022. Take them to your local pharmacy which will dispose of them for you. This is not a complete list of possible side effects. Along with its needed effects, a medicine may cause some unwanted effects. What special dietary instructions should I follow? Is not subject to the Controlled Substances Act. Eur Heart J. Can isosorbide mononitrate cause problems? Do not keep out-of-date or unwanted medicines. Upgrade to Patient Pro Medical Professional? Some people feel dizzy or fall when changing positions, such as going from sitting to standing. Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. Danshen. Patient is a UK registered trade mark. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks (chest pain). Natural Medicines. If you suffer headaches when taking Isosorbide mononitrate, be patient. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The extended-release tablet usually is taken once daily in the morning. If you experience any other symptoms which you think may be due to the medicine, please speak with your doctor or pharmacist for further advice. Do not take more or less of it or take it more often than prescribed by your doctor. Saw palmetto. Registered in England and Wales. prevention of anginal chest pain associated with coronary artery disease, prevent bleeding varicose vein in the esophagus. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets; Merus Labs Luxco S.a.R.L, The electronic Medicines Compendium. Accessed Sept. 7, 2022. The short-acting tablet is usually taken as 10 mg to 40 mg by mouth 2 or 3 times daily with at least a 14 hour period of time per day where you don't take any doses. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). What side effects can this medication cause? Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. Generic alternatives may be available. Accessed Sept. 7, 2022. Please see a good cardiologist, get admitted, get checked thoroughly. Limited data from animal studies indicate no adverse effects on the pregnancy or the unborn child. WebMD does not provide medical advice, diagnosis or treatment. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. If you have ever had an allergic reaction to a medicine. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. This survey is being conducted by the WebMD marketing sciences department. Take extra precautions to avoid falling during your treatment with isosorbide. To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. Anti-ischemic and anti-anginal effects of controlled-release and conventional isosorbide-5-mononitrate in stable angina pectoris. You can start a phase IV clinical trial to monitor Isosorbide mononitrate safety and effectiveness. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Sildenafil ( Viagra ), tadalafil ( Cialis ), avanafil ( Stendra ),and vardenafil ( Levitra) increase the blood pressure lowering effects of isosorbide mononitrate and may cause excessive reductions in blood pressure. Alcohol or marijuana (cannabis) can make you more dizzy. This product may contain inactive ingredients, which can cause allergic reactions or other problems. 41% of reviewers reported a positive effect, while 50% reported a negative effect. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. Trapidil is as effective as isosorbide-dinitrate for treating stable angina pectoris: a multinational, multicenter, double-blind, randomized study. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. 88 ratings on Drugs.com. Commonly reported side effects include: See also: isosorbide mononitrate side effects in more detail. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or . Your doctor may tell you to take a pain reliever to treat your headaches. It is important to take the drug at the same times each day. Methods: Accessed Sept. 7, 2022. If you have an underactive thyroid gland. Does isosorbide mononitrate (Monoket) affect your kidneys? Herbal medications in cardiovascular medicine. Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. Along with its needed effects, a medicine may cause some unwanted effects. We comply with the HONcode standard for trustworthy health information. https://naturalmedicines.therapeuticresearch.com. While both isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat) are both nitrate vasodilators, they are not the same medication. Coenzyme Q-10 Natural Medicines. It works by relaxing and widening blood vessels so blood can flow more easily to the heart.This medication will not relieve chest pain once it occurs. Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. It is important that you follow the instructions your doctor gives to you about when to take your doses. This medicine is available only with your doctor's . Ask your doctor before using aspirin together with alcohol. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Take the missed dose as soon as you remember it. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). To view a report comparing 3 (or more) medications, please sign in or create an account. Who should not take Isosorbide Mononitrate? Elantan, Imdur, Isotard, Monomax, Tardisc, Xismox. Aspirin relieves pain and inflammation and helps to thin the blood. Modified-release nitrate preparations: use a once-daily dose to maintain a nitrate-low period and thus minimize tolerance. Keep this medication in the container it came in, tightly closed, and out of reach of children. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Isosorbide dinitrate (Isordil) is available as both a short-acting tablet and long-acting capsule. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. Talk to your pharmacist for more details. (2) One in 3 patients never experienced headache from the given dosages. the unsubscribe link in the e-mail. You may report side effects to the FDA at 1-800-FDA-1088. It can cause your blood pressure to become dangerously low. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. What should I know regarding pregnancy, nursing and administering Isosorbide Mononitrate to children or the elderly?
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